刘洪鑫，男，博士，硕士生导师。2018年毕业与中国科学院成都生物研究所，同年进入温州大学化学与材料工程学院。主要研究方向：(1)有机小分子不对称催化合成；(2)基于DNA体系的仿生不对称催化；(3)手性药物开发设计。在Org. Lett.,Org. Chem. Front.,Chem. Commun.，Chem-Eur. J.,Frontiers in Chemistry等国际期刊发表多篇论文。现主持浙江省自然科学基金青年项目1项，浙江省教育厅基金项目1项，温州市科技计划项目1项，温州市科协服务创新项目1项。申报发明专利12项，已授权国内专利4项，美国专利1项。参与编写出版专著1部:现代仪器分析研究性案例精选(科学出版社)。

主持在研项目：

浙江省自然科学基金青年项目(LQ19B020004)，手性含氢键羧酸盐催化剂的设计、合成及应用研究，10万。

浙江省教育厅基金项目(Y201839490)，新型手性羧酸盐催化剂的设计及应用研究，1万。

温州市科技计划项目(G20180015)，新型手性催化剂在药物合成开发中的应用研究，10万。

温州市科协服务创新项目(kjfw35),抗肿瘤活性分子UCS1025A片段合成研究，6万。

研究成果：

13. Xin Qin, Chaofei Wu, Fanyun Lu, Zhan-Yong Wang*, Jun Jiang*,Hongxin Liu*The Aldol Reaction of α-Ketoamide with α,β-Unsaturated Ketone in KOH Aqueous MediumChemistrySelect,2022, 7, DOI: 10.1002/slct.202104146.

12. Chaofei Wu, Bolun Hu,Hongxin Liu*, Jun Jiang*, Jimin Kim* Arginine-Catalyzed Henry Reaction of α-Keto Amides with Nitromethane on WaterChemistrySelect,2022, 7, DOI: 10.1002/slct.202104433.

11. Zhan-Yong Wang*, Fumin Shen, Ting Yang, Jun-Kai Zhang, Rongxiang Chen, Kai-Kai Wang*, Hongxin Liu* Carbene-Catalyzed Three-Component Cascade Reaction of Benzofuran-2-ones and Enals: Construction of Spirobenzofuranone-δ-lactonesAsian J. Org. Chem.,2021, 10, 3293-3296.

10. Fu-Hua Qin, Qing-Qing Kang, Jun-Yao Zhang, Sen-Jie Hu, Yi Liu, Yiping Ruan∗, Hongxing Zheng, Yi-Lin Fang,Hongxin Liu*, Wen-Ting Wei* Radical Cyclization of Olefinic Amides through α-C(sp³)–H Functionalization of Ketones under Catalyst-, Ligand-, and Base-Free ConditionsSynlett,2021, 32, 905-912.

9. Renyuan Chen, Caidie Xu, Yihao Lei,Hongxin Liu*, Yabin Zhu, Jianfeng Zhang, Long Xu* Facile construction of a family of supramolecular gels with good levofloxacin hydrochloride loading capacityRSC Adv.,2021, 11, 12641-12648.

8. Yi-Lin Liu, Yue-Jun Ouyang*, Hongxing Zheng,Hongxin Liu*, Wen-Ting We* Recent advances in acyl radical enabled reactions between aldehydes and alkenesChem. Commun.,2021, 57, 6111-6120.

7. Caidie Xu, Renlu Han,Hongxin Liu*, Yabin Zhu, Jianfeng Zhang, Long Xu* Construction of Polymeric Micelles for Improving Cancer Chemotherapy by Promoting the Production of Intracellular Reactive Oxygen Species and Self-Accelerating Drug ReleaseChemistrySelect2021, 6, 3277-3285.

6. Qing-Qing Kang, Ya-Nan Meng, Jun-Hao Zhang, Long Li, Guo-Ping Ge*, Hongxing Zheng,Hongxin Liu* Wen-Ting Wei * Iron-catalyzed oxidative cyclization of olefinic 1,3-dicarbonyls with ketone C(sp³)-H bonds: facile access to 2,3-dihydrofuransNew J. Chem.,2021,45, 13639-13643.

5. Zhan-Yong Wang, Ting Yang, Kai-Kai Wang, Rongxiang Chen, Menghan Liu, Hongxin Liu* Oxidative N-heterocyclic carbene catalyzed formal [3+3] annulation reaction of enals with benzofuran-3-ones: efficient access to benzofuran fused δ-lactones Org. Chem. Front, 2020, 7, 1011-1015.

4. Na Wang, Hongxin Liu*, Hang Gao, Jiafeng Zhou, Longzhangdi Zheng, Juan Li, Hong-Ping Xiao, Xinhua Li, Jun Jiang* Ni(II)-Catalyzed Enantioselective Synthesis of β-Hydroxy Esters with Carboxylate Assistance Org. Lett., 2019, 21, 6684-6689.

3. Chaofei Wu, Juan Li, Hong-Ping Xiao, Xinhua Li, Hongxin Liu*, Jun Jiang* Chiral H-1 NMR of Atropisomeric Quinazolinones With Enantiopure, Frontiers in Chemistry, 2018. 8. 17. 6: 0-300.

2. Zheng Zhu, Quanquan Wu, Chong-Xing Liu, Zhannan Yang*, Hongxin Liu* Catalyst-free benzylic C(sp(3))-H functionalization of methyl quinolines with tryptanthrins, Synthetic. Commun. , 2018, 48(9), 1092-1098.

1.Hongxin Liu, Guangxun Li*, Ying-wei Wang, Shiqi Zhang, Zhuo Tang* Bioinspired Catalysis: Self-Assembly of Protein and DNA as Catalyst for the Aldol Reaction in Aqueous Media, Synlett., 2018, 29(5), 560-565.

联系方式：17326791213，hongxin-107@163.com